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Aminophenoler

Organiske forbindelser, der består af en phenolring med en aminofunktionel gruppesubstitution; aminofunktionelle grupper består af et nitrogenatom bundet til hydrogenatomer via enkeltbindinger.

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1 – 15 af 19 Resultater
1

BN82002, MedChemExpress

MedChemExpress BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. BN82002 displays ∼20-fold greater selectivity over CD45 tyrosine phosphatase.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale BN82002
Formel vægt 359.42
Opløselighedsinformation DMSO : ≥ 150 mg/mL (417.34 mM)
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 359.42
CAS 396073-89-5
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL OC1=C(CN(C)CCC2=CC=C([N+]([O-])=O)C=C2)C=C(N(C)C)C=C1OC
Renhedsgrad noter Research
Molekylær formel C19H25N3O4
Til brug med (applikation) Cancer-programmed cell death
2

ZL0420, MedChemExpress

MedChemExpress ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale ZL0420
Formel vægt 296.32
Opløselighedsinformation DMSO : 125 mg/mL (421.84 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve Orange
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 296.32
CAS 2230496-80-5
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL OC1=CC(N)=C(/N=N/C2=CC(CCC(N3)=O)=C3C=C2)C=C1C.[(E)]
Renhedsgrad noter Research
Molekylær formel C16H16N4O2
Til brug med (applikation) COVID-19-immunoregulation
3

OTS514, MedChemExpress

MedChemExpress OTS514 is a highly potent TOPK inhibitor with an IC50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells. OTS514 induces cell cycle arrest and apoptosis.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale OTS514
Formel vægt 364.46
Opløselighedsinformation DMSO : 100 mg/mL (274.38 mM; Need ultrasonic)
Procent renhed 98.15%
Fysisk form Solid
Farve Earth Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 364.46
CAS 1338540-63-8
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4
Renhedsgrad noter Research
Molekylær formel C21H20N2O2S
Til brug med (applikation) Cancer-Kinase/protease
4

inS3-54A18, MedChemExpress

MedChemExpress inS3-54A18 is a potent STAT3 inhibitor, with anti-cancer properties.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale inS3-54A18
Formel vægt 373.83
Opløselighedsinformation DMSO : ≥ 150 mg/mL (401.25 mM)
Procent renhed 99.83%
Fysisk form Solid
Farve Orange
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 373.83
CAS 328998-53-4
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C1N(C2=CC=C(O)C=C2)C(C3=CC=CC=C3)=C/C1=C/C4=CC=C(Cl)C=C4
Renhedsgrad noter Research
Molekylær formel C23H16ClNO2
Til brug med (applikation) Cancer-Kinase/protease
5

Lavendustin A, MedChemExpress

MedChemExpress Lavendustin A (RG-14355), isolated from Streptomyces Griseolavendus, is a potent, specific and ATP-competitive inhibitor of tyrosine kinase, with an IC50 of 11 ng/mL for EGFR-associated tyrosine kinase. It suppresses VEGF-induced angiogenesis and blocks the induction of LTPGABA-A.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Lavendustin A
Formel vægt 381.38
Opløselighedsinformation DMSO : ≥ 250 mg/mL (655.51 mM)
Procent renhed 95.0%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 381.38
CAS 125697-92-9
Synonym RG-14355
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)C1=CC(N(CC2=CC(O)=CC=C2O)CC3=CC=CC=C3O)=CC=C1O
Renhedsgrad noter Research
Molekylær formel C21H19NO6
Til brug med (applikation) Cancer-Kinase/protease
6

Acetaminophen metabolite 3-hydroxy-acetaminophen, MedChemExpress

MedChemExpress 3-hydroxy-acetaminophen is a metabolite of Acetaminophen, which is a pain medicine.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Acetaminophen metabolite 3-hydroxy-acetaminophen
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 167.16
Opløselighedsinformation DMSO : 250 mg/mL (1495.57 mM; Need ultrasonic)
Procent renhed 99.03%
Fysisk form Solid
Farve Gray
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 167.16
CAS 37519-14-5
Synonym 3-Hydroxyacetaminophen
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL OC1=C(O)C=C(NC(C)=O)C=C1
Renhedsgrad noter Research
Molekylær formel C8H9NO3
Til brug med (applikation) Neuroscience-Neuromodulation
7

Balsalazide, MedChemExpress

MedChemExpress Balsalazide could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Balsalazide
Formel vægt 357.32
Opløselighedsinformation DMSO : 100 mg/mL (279.86 mM; Need ultrasonic)
Procent renhed 99.2%
Fysisk form Solid
Farve Orange
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 357.32
CAS 80573-04-2
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)C1=CC(/N=N/C2=CC=C(C(NCCC(O)=O)=O)C=C2)=CC=C1O
Renhedsgrad noter Research
Molekylær formel C17H15N3O6
Til brug med (applikation) COVID-19-immunoregulation
8

SKI II, MedChemExpress

MedChemExpress SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale SKI II
Sundhedsfare 1 H302
Formel vægt 302.78
Opløselighedsinformation DMSO : ≥ 100 mg/mL (330.27 mM)
Procent renhed 99.88%
Fysisk form Solid
Farve White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 302.78
CAS 312636-16-1
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL OC1=CC=C(NC2=NC(C3=CC=C(Cl)C=C3)=CS2)C=C1
Renhedsgrad noter Research
Molekylær formel C15H11ClN2OS
Til brug med (applikation) Cancer-Kinase/protease
9

Propyl pyrazole triol, MedChemExpress

MedChemExpress Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).

ENCOMPASS_PREFERRED
10

S55746, MedChemExpress

MedChemExpress S55746 (BCL201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BCL201) has antitumor activity with low toxicity.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale S55746
Formel vægt 710.82
Opløselighedsinformation DMSO : 50 mg/mL (70.34 mM; Need ultrasonic)
Procent renhed 98.93%
Fysisk form Powder
Farve Light Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 710.82
CAS 1448584-12-0
Synonym BCL201
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9
Renhedsgrad noter Research
Molekylær formel C43H42N4O6
Til brug med (applikation) Cancer-programmed cell death
11

Osalmid, MedChemExpress

MedChemExpress Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Osalmid
Sundhedsfare 1 H302∣H315∣H319
Formel vægt 229.23
Opløselighedsinformation DMSO : ≥ 100 mg/mL (436.24 mM)
Procent renhed 99.85%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 229.23
CAS 526-18-1
Synonym Oxaphenamide 4'-Hydroxysalicylanilide
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(NC1=CC=C(O)C=C1)C2=CC=CC=C2O
Renhedsgrad noter Research
Molekylær formel C13H11NO3
Til brug med (applikation) COVID-19-anti-virus
12

Fenretinide, MedChemExpress

MedChemExpress Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Fenretinide
Sundhedsfare 1 H302+H312+H332∣H315∣H319∣H335∣H360
Formel vægt 391.55
Opløselighedsinformation DMSO : ≥ 130 mg/mL (332.01 mM)
Procent renhed 99.08%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 391.55
CAS 65646-68-6
Synonym 4-HPR
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL CC(/C=C/C=C(/C=C/C1=C(CCCC(C)1C)C)C)=C\C(NC2=CC=C(O)C=C2)=O
Renhedsgrad noter Research
Molekylær formel C26H33NO2
Til brug med (applikation) Cancer-programmed cell death
13

S55746 hydrochloride, MedChemExpress

MedChemExpress S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale S55746 hydrochloride
Formel vægt 747.28
Opløselighedsinformation DMSO : 200 mg/mL (267.64 mM; Need ultrasonic)
Procent renhed 98.69%
Fysisk form Powder
Farve Light Yellow
Grad Research
Anbefalet opbevaring 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol) 747.28
CAS 1448525-91-4
Synonym BCL201 hydrochloride
Holdbarhed 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9.Cl
Renhedsgrad noter Research
Molekylær formel C43H43ClN4O6
Til brug med (applikation) Cancer-programmed cell death
14

5-Lipoxygenase-In-1, MedChemExpress

MedChemExpress 5-Lipoxygenase-In-1 is a 5-Lipoxygenase inhibitor extracted from patent EP 331232 A2, table 4, compound example 4.10.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale 5-Lipoxygenase-In-1
Formel vægt 424.56
Opløselighedsinformation DMSO : 250 mg/mL (588.84 mM; Need ultrasonic)
Procent renhed 98.07%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 424.56
CAS 125235-15-6
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(C(C)(C)N1CC)N(C2=CC=C(N3CCN(C4=CC=C(O)C=C4)CC3)C=C2)C1=S
Renhedsgrad noter Research
Molekylær formel C23H28N4O2S
Til brug med (applikation) COVID-19-immunoregulation
15

JANEX-1, MedChemExpress

MedChemExpress JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale JANEX-1
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 297.31
Opløselighedsinformation DMSO : ≥ 100 mg/mL (336.35 mM)
Procent renhed 99.6%
Fysisk form Solid
Farve Gray
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 297.31
CAS 202475-60-3
Synonym WHI-P131 Jak3 inhibitor I
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1
Renhedsgrad noter Research
Molekylær formel C16H15N3O3
Til brug med (applikation) Cancer-Kinase/protease