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    1. Home
    2. Biotech Solutions
    3. Cell and Gene Therapies
    4. Gene Editing Solutions

    Gene Editing Solutions

    Precision and efficiency are vital in order to minimize off-target effects and unintended modifications. Get the best products for the best results.

    1. Vector Construction: Plasmid Development
    2. Vector Construction: Amplification
    3. Viral Vector Production: Mammalian or Insect Cell Platforms
    4. Viral Vector Production: Gene Modification
    5. Vector Purification: Nucleic Acid Isolation and Purification
    6. Vector Purification: Chromatography, Filtration, and Fluid Transfer Solutions

    Gene editing is an exciting and groundbreaking technology that allows scientists to make precise changes to the DNA of living organisms. It holds tremendous promise for a wide range of applications, from treating genetic diseases to improving crop yields and enhancing our understanding of the natural world.

    At the heart of gene editing is the ability to modify specific genes within an organism's DNA. This precise editing process enables researchers to add, remove, or alter genetic material with unprecedented accuracy.

    What makes gene editing particularly exciting is its potential to revolutionize various fields. In medicine, gene editing holds the promise of treating genetic disorders by correcting faulty genes responsible for disease. It could offer new avenues for developing targeted therapies and personalized medicine.

    Moreover, gene editing can aid in scientific research by providing a powerful tool to study gene function and unravel the complexities of genetic interactions. By precisely modifying genes in model organisms, researchers can better understand how specific genes contribute to development, disease, and various biological processes.

    1. Vector Construction: Plasmid Development


    Top Products

    Invitrogen™ Platinum™ SuperFi II DNA Polymerase

    For highest confidence in PCR sequence accuracy

    Invitrogen™ Platinum™ SuperFi II DNA Polymerase

    Axygen™ Maxygene II Thermal Cycler

    Improved workflow over traditional gradient cyclers

    Axygen™ Maxygene II Thermal Cycler

    Gibco™ Bacto™ CD Supreme Fermentation Production Medium (FPM)

    Increases growth and production yields

    Gibco Bacto CD Supreme Fermentation Production Medium (FPM):Microbiological Gibco™ Bacto™ CD Supreme Fermentation Production Medium (FPM)

    Thermo Scientific™ CO₂ Resistant Shakers

    Get reliable around-the-clock operation to keep your cells flourishing

    Thermo Scientific™ CO2 Resistant Shakers

    Featured Products

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    Catalog Number 4918428

    Invitrogen™ Luria Broth Base (Miller's LB Broth Base), powder
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    Catalog Number 4529505

    Thermo Scientific™ Heratherm™ Compact Microbiological Incubators
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    Catalog Number 4897964

    Gibco™ Bacto™ Peptone
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    Essential Categories

    View All Competent Cells
    View All Restriction Enzymes
    View All Orbital Shakers

    2. Vector Construction: Amplification


    Top Products

    Gibco™ FreeStyle™ F17 Expression Medium

    Supports growth and transfection of HEK293 cells in suspension

    Gibco™ FreeStyle™ F17 Expression Medium

    BINDER™ Series CBF CO₂ Incubator, with Hot Air Sterilization and Humidity Regulation

    Maximum flexibility and humidity control

    BINDER™ Series CBF CO2 Incubator, with Hot Air Sterilization and Humidity Regulation

    Thermo Scientific™ TSX Series Ultra-Low Temperature Freezers

    Meet the highest standards in reliability, sustainability, and temperature management

    Thermo Scientific™ TSX Series Ultra-Low Freezers

    Cole-Parmer™ MP-200 Series Stuart™ Digital Melting Point Apparatus

    Designed for safe, easy, and accurate operation

    Cole-Parmer™ MP-200 Series Stuart™ Digital Melting Point Apparatus

    Featured Products

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    Catalog Number 11510866

    Invitrogen™ pcDNA™3.1 (+) Mammalian Expression Vector
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    Catalog Number 7188044

    Invitrogen™ Second Strand cDNA Synthesis Kit
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    Catalog Number 4521711

    Thermo Scientific™ FastDigest EcoRI
    Viewing 1-3 of 3

    Essential Categories

    View All DNA Cloning, Mapping, and Mutagenesis Products
    View All CO₂ Incubators
    View All Gene Reporter Systems

    3. Viral Vector Production: Mammalian or Insect Cell Platforms


    Top Products

    Gibco™ Viral Production Medium

    Developed for growth and transfection of Viral Production Cells 2.0

    Gibco™ Viral Production Medium

    Gibco™ Viral Production Cells 2.0

    Enables production of high AAV titers

    Gibco™ Viral Production Cells 2.0

    Thermo Scientific™ Sorvall™ BIOS 16 Bioprocessing Centrifuge

    Get your research done more quickly, consistently, and with powerful reliability

    Thermo Scientific™ Sorvall™ BIOS 16 Bioprocessing Centrifuge

    Thermo Scientific™ Sorvall LYNX 6000 Superspeed Centrifuge

    Optimal for high performance separation needs from academic research to bioproduction

    Thermo Scientific™ Sorvall LYNX 6000 Superspeed Centrifuge

    Featured Products

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    Catalog Number 7113083

    Gibco™ LV-MAX™ Production Medium
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    Catalog Number 4525461

    Thermo Scientific™ Nunc™ Cell Factory™ System
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    Catalog Number 15829081

    Gibco™ LV-MAX™ Lentiviral Production System
    Viewing 1-3 of 3

    Essential Categories

    View All Vector Production Cell Culture Media
    View All Low Speed Floor Model Centrifuges
    View All Cell Culture Flasks

    4. Viral Vector Production: Gene Modification


    Top Products

    Applied Biosystems™ Absolute Q™ Viral Titer 10

    Enable easy and accurate quantification of viral vectors

    ABI Applied Biosystems ABSOLUTE Q VIRAL TITER 10

    Gibco™ AAV-MAX Transfection Kit

    Saves time and reduces cost

    Gibco™ AAV-MAX Transfection Kit

    Invitrogen™ Lipofectamine™ 3000 Transfection Reagent

    Superior transfection performance due to advanced nanoparticle technology

    Invitrogen™ Lipofectamine™ 3000 Transfection Reagent

    Invitrogen™ TrueCut™ Cas9 Protein v2

    Delivers maximum editing efficiency

    Invitrogen™ TrueCut™ Cas9 Protein v2

    Featured Products

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    Catalog Number 4919917

    Gibco™ Opti-MEM™ I Reduced Serum Medium
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    Catalog Number 10431915

    Invitrogen™ Neon™ Transfection System
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    Catalog Number 7075867

    Gibco™ ExpiFectamine™ 293 Transfection Kit
    Viewing 1-3 of 3

    Essential Categories

    View All Transfection Reagents
    View All Classical and Basal Cell Culture Media
    View All Modifying Enzymes

    5. Vector Purification: Nucleic Acid Isolation and Purification


    Top Products

    Thermo Scientific™ DNAPac™ RP Columns

    Excellent separation under a broad range of pH, temperature, and mobile phase compositions

    Thermo Scientific™ DNAPac™ RP Columns

    Applied Biosystems™ QuantStudio™ Absolute Q Package, including Digital PCR System

    Accurate measurement of viral titers in gene therapy

    Applied Biosystems™ QuantStudio™ Absolute Q Package, including Digital PCR System, desktop PC, Smart Start training and 1 Year extended warranty

    Triton X-100, Thermo Scientific Chemicals

    Proven cost-effective, efficient cell lysis for AdV and AAV preparations

    Triton X-100, Thermo Scientific Chemicals

    Macherey-Nagel™ NucleoBond™ PC EF, kit for endotoxin-free plasmid DNA

    Isolation of ultra-pure endotoxin-free plasmid DNA

    Macherey-Nagel™ NucleoBond™ PC EF, kit for endotoxin-free plasmid DNA

    Featured Products

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    Catalog Number 15442203

    Implen™ NanoPhotometer™ N60 Micro-Volume UV-VIS Spectrophotometer
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    Catalog Number 8929004

    Thermo Scientific™ KingFisher Apex Purification Systems
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    Catalog Number 7180723

    Thermo Scientific™ CaptureSelect™ AAVX Ligand Leakage ELISA
    Viewing 1-3 of 3

    Essential Categories

    View All HPLC Columns
    View All DNA Extraction and Purification Products
    View All Protein Purification Reagents and Kits

    6. Vector Purification: Chromatography, Filtration, and Fluid Transfer Solutions


    Top Products

    Thermo Scientific™ SureSTART™ 2 mL Polypropylene Screw Top Microvials

    Analyse polar compounds/analytes with ease

    Thermo Scientific™  SureSTART™ 2 mL Polypropylene Screw Top Microvials for <2 mL Samples, Level 1 Everyday Analysis

    Corning™ X‐LAB™ System

    Separate and harvest a programmable volume of target cell populations from blood and blood products

    Corning™ X‐LAB™ System

    DWK Life Sciences DURAN™ Filtering Apparatus, with Receiving Flask and Funnel

    Suitable for a wide range of vacuum filtration applications

    DWK Life Sciences DURAN™ Filtering Apparatus, with receiving flask and funnel

    Axygen™ Gel Documentation Systems

    Easily capture publication quality, 16 bit TIFF images

    Axygen™ Gel Documentation Systems

    Featured Products

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    Catalog Number 17184771

    Cytiva Minimate; EVO Tangential Flow Filtration (TFF) System
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    Catalog Number 10799731

    Sartorius Minisart™ SRP Syringe Filters, Nonsterile
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    Catalog Number 10489553

    Fisher Chemical Acetonitrile, Optima™ LC/MS Grade, Fisher Chemical™
    Viewing 1-3 of 3

    Essential Categories

    View All Filter Units
    View All Bioprocess System Bags and Liners
    View All Filtration Membrane Discs

    Related Resources


    Your Partners in Cancer Research

    Fighting cancer is more than just research. To many it's a passion and a calling to make the world a better place, and, for far too many, it's personal.

    Download
    Your Partners in Cancer Research

    Other Applications


    Stem Cell Therapy Solutions

    Key tools and technologies to advance groundbreaking stem cell research.

    Learn More
    Stem Cell Therapy

    CAR T-Cell Therapy Solutions

    Comprehensive tools that span your workflow, from research to the clinic.

    Learn More
    CAR T-Cell Therapy Solutions

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