HPLC Columns

Columns used for separation of biomolecules and organic or inorganic analytes; includes normal phase, reversed phase, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.

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Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

Pricing and Availability

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Thermo Scientific™ Hypersil™ ODS C18 Columns

Use as a general purpose C18 phase for acidic and neutral analytes.

Pricing and Availability
Specifications

Pore Size	120 Å
Carbon Load	10%
Stationary Phase	C18
Temperature	60°C
Phase	Reversed Phase
Endcapped	Yes
Column Type	Reversed Phase
pH	2 to 8
Surface Area	170 m²/g
USP Type	L1

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Thermo Scientific™ Hypersil™ BDS C18 Columns

Use as a robust, general-purpose column for a wide range of applications in QC/QA labs.

Pricing and Availability
Specifications

Carbon Load	11%
Stationary Phase	C18
Phase	Reversed Phase
Endcapped	Yes
Column Type	Reversed Phase
Surface Area	170 m²/g
USP Type	L1

Thermo Scientific™ Acclaim™ 120 C18 Columns

Use these high-efficiency reversed phase C18 columns for maximum resolution in a wide variety of applications.

Pricing and Availability
Specifications

Pore Size	120 Å
Carbon Load	18%
Stationary Phase	C18
Temperature	60°C
Endcapped	Yes
Column Type	Reversed Phase
pH	2 to 8
Surface Area	300 m²/g
USP Type	L1

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Thermo Scientific™ Accucore™ Vanquish™ C18+ UHPLC Columns, 1.5μm

Use the 1.5μm solid core particles of these columns with the Vanquish UHPLC system for unique high-efficiency, high-resolution analyses.

Pricing and Availability
Specifications

Pore Size	80 Å
Particle Size	1.5 μm
Carbon Load	6.5%
Stationary Phase	C18
Temperature	70°C
Phase	Reversed Phase
Endcapped	Yes
Column Type	Reversed Phase
Diameter (Metric)	2.1 mm
pH	2 to 9
Surface Area	110 m²/g
USP Type	L1

Thermo Scientific™ Hypersil™ PREP ODS C18 HPLC Columns

Perfect for routine workflows, our Hypersil PREP ODS preparative LC column is a general purpose C18 used in a broad range of USP L1 applications.

Pricing and Availability
Specifications

Pore Size	130 Å
Carbon Load	10%
Stationary Phase	C18
Temperature	60°C
Phase	Reversed Phase
Endcapped	Yes
Packing Material	Spherical, Fully Porous Silica
Column Type	Reversed Phase
pH	2 to 8
Surface Area	195 m²/g
USP Type	L1

Thermo Scientific™ Accucore™ aQ C18 Polar Endcapped HPLC Columns

Use this column, with its specially designed solid core, for the separation of compounds in highly aqueous mobile phases.

Pricing and Availability
Specifications

Pore Size	80 Å
Stationary Phase	C18
Temperature	70°C
Phase	Reversed Phase
Endcapped	Polar
Column Type	Reversed Phase
Surface Area	130 m²/g
Max. Pressure	14500 psi (1000 bar)
Particle Size	2.6 μm
Carbon Load	9%
Packing Material	Spherical, Solid Core, Ultrapure Silica
pH	2 to 9
Particle Shape	Spherical Solid Core
Product Line	Accucore
USP Type	L1

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Thermo Scientific™ Hypersil™ Silica HPLC Columns

Use the efficient and selective Thermo Scientific™ Hypersil™ Silica LC Columns for normal phase chromatography of nonpolar and moderately polar organic compounds.

Pricing and Availability
Specifications

Pore Size	120 Å
Stationary Phase	Silica
Temperature	60°C
Phase	Normal Phase
Column Type	Normal Phase
pH	2 to 8
Surface Area	170 m²/g
USP Type	L3

Thermo Scientific™ BetaSil™ Silica HPLC Columns, 5μm Particle Size

Experience a powerful column for separating non-polar and moderately polar compounds based on 100Å high purity silica and designed for small molecule analysis.

Pricing and Availability
Specifications

Pore Size	100 Å
Particle Size	5 μm
Stationary Phase	Silica
Temperature	35°C
Phase	Normal Phase
Packing Material	Spherical, Fully Porous Silica
Column Type	Normal Phase
Surface Area	310 m²/g
USP Type	L3

Thermo Scientific™ Syncronis™ C18 Columns

Use for hydrophobic interaction reversed-phase separations.

Pricing and Availability
Specifications

Pore Size	100 Å
Carbon Load	16%
Stationary Phase	C18
Temperature	60°C
Phase	Reversed Phase
Endcapped	Yes
Column Type	Reversed Phase
pH	2 to 9
Surface Area	320 m²/g
USP Type	L1

Thermo Scientific™ BetaBasic™ 18 HPLC Columns, 3μm Particle Size

Available in limited dimensions. Please contact Customer Service for more details.

Pricing and Availability
Specifications

Pore Size	150 Å
Particle Size	3 μm
Carbon Load	13%
Stationary Phase	C18
Phase	Reversed Phase
For Use With	LC/MS, APCI
Endcapped	Yes
Packing Material	Silica
Column Type	Reversed Phase
pH	2 to 12
Surface Area	200 m²/g
USP Type	L1
Column Format	Analytical Column

Thermo Scientific™ Hypersil™ PREP HS C18 HPLC Columns

Maximize retention and loading with Hypersil PREP HS C18 prep LC reversed phase columns which offers high loading capacity and suitable for USP-L1 Applications.

Pricing and Availability
Specifications

Pore Size	100 Å
Carbon Load	15%
Stationary Phase	C18
Temperature	60°C
Phase	Reversed Phase
Endcapped	Yes
Packing Material	Spherical, Fully Porous, Ultrapure Silica
Column Type	Reversed Phase
pH	2 to 9
Surface Area	350 m²/g
USP Type	L1

Thermo Scientific™ Acclaim™ HILIC-10 HPLC Columns

Use this HILIC column to retain and separate highly polar molecules that are unretained by reversed-phase chromatography.

Pricing and Availability
Specifications

Pore Size	120 Å
Carbon Load	8%
Stationary Phase	Proprietary
Temperature	70°C
Phase	HILIC
For Use With	LC/MS
Endcapped	Yes
Column Type	HILIC
pH	2 to 8
Surface Area	300 m²/g
Product Line	Acclaim

Thermo Scientific™ SurePac™ Bio 550 SEC MDi™ HPLC Columns

Experience the future of Size-Exclusion Chromatography (SEC) with SurePac™ Bio 550 SEC MDi™ analytical columns and guards exclusively designed to deliver robust and reproducible performance at high resolution and throughput to accelerate your therapeutics analysis process.

Pricing and Availability
Specifications

Particle Size	3 μm
Stationary Phase	Proprietary
Temperature	20°C to 60°C
Phase	Size Exclusion
Packing Material	Monodisperse Silica Resin
pH	2 to 8
Quantity	1 Ea.
Technique	SEC

Thermo Scientific™ Acclaim™ SEC-1000 Size Exclusion Chromatography HPLC Columns

Separate water-soluble polymers and oligomers with the Acclaim family of resin-based, high-performance, size-exclusion chromatography columns.

Pricing and Availability
Specifications

Pore Size	1000 Å
Particle Size	7 μm
Stationary Phase	Proprietary
Temperature	60°C
Phase	Size Exclusion
Endcapped	Yes
Column Type	Size Exclusion
pH	2 to 12
Quantity	Each
Green Features	Responsibly packaged
Technique	Bio-LC
Particle Shape	Spherical
Product Line	Acclaim

HPLC Columns

HPLC Columns

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Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns SureTRACESupports traceability with guaranteed access to certificates and proactive change notifications.Learn More

Thermo Scientific™ Accucore™ Vanquish™ C18+ UHPLC Columns, 1.5μm SureTRACESupports traceability with guaranteed access to certificates and proactive change notifications.Learn More

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Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns

Thermo Scientific™ Accucore™ Vanquish™ C18+ UHPLC Columns, 1.5μm