CAS RN 66701-25-5

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E-64

CAS: 66701-25-5 Molekylær formel: C15H27N5O5 Molekylvægt (g/mol): 357.41 MDL nummer: MFCD00080261,MFCD00080261 InChI nøgle: LTLYEAJONXGNFG-HBNTYKKESA-N Synonym: d09fgq,l-3-trans-carboxy-oxiran-2-carbonyl-leu-agmatin,trans-epoxysuccinyl-leucylamido-4-guanidino butane,3-1-4-carbamimidamidobutyl carbamoyl-3-methylbutyl carbamoyl oxirane-2-carboxylic acid,3-1-4-diaminomethylideneamino butylamino-4-methyl-1-oxopentan-2-yl carbamoyl oxirane-2-carboxylic acid PubChem CID: 4641099 IUPAC navn: 3-[[1-[4-(diaminomethylidenamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxiran-2-carboxylsyre SMIL: CC(C)C[C@H](NC(=O)[C@@H]1O[C@H]1C(O)=O)C(=O)NCCCCN=C(N)N

Pris og tilgængelighed
Tekniske data

MDL nummer	MFCD00080261,MFCD00080261
PubChem CID	4641099
Molekylvægt (g/mol)	357.41
CAS	66701-25-5
Synonym	d09fgq,l-3-trans-carboxy-oxiran-2-carbonyl-leu-agmatin,trans-epoxysuccinyl-leucylamido-4-guanidino butane,3-1-4-carbamimidamidobutyl carbamoyl-3-methylbutyl carbamoyl oxirane-2-carboxylic acid,3-1-4-diaminomethylideneamino butylamino-4-methyl-1-oxopentan-2-yl carbamoyl oxirane-2-carboxylic acid
SMIL	CC(C)C[C@H](NC(=O)[C@@H]1O[C@H]1C(O)=O)C(=O)NCCCCN=C(N)N
IUPAC navn	3-[[1-[4-(diaminomethylidenamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxiran-2-carboxylsyre
InChI nøgle	LTLYEAJONXGNFG-HBNTYKKESA-N
Molekylær formel	C15H27N5O5

E 64, TRC

CAS: 66701-25-5 Molekylær formel: C15 H27 N5 O5 Molekylvægt (g/mol): 357.41 Synonym: (2S,3S)-3-[[[(1S)-1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid,[2S-[2α,3β(R*)]]-3-[[[1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid,Proteinase Inhibitor E 64,trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)Butane IUPAC navn: (2R,3R)-3-[[(2S)-1-(4-carbamimidamidobutylamino)-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid SMIL: CC(C)C[C@H](NC(=O)[C@@H]1O[C@H]1C(=O)O)C(=O)NCCCCNC(=N)N

Pris og tilgængelighed
Tekniske data

Molekylvægt (g/mol)	357.41
CAS	66701-25-5
Synonym	(2S,3S)-3-[[[(1S)-1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid,[2S-[2α,3β(R*)]]-3-[[[1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid,Proteinase Inhibitor E 64,trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)Butane
SMIL	CC(C)C[C@H](NC(=O)[C@@H]1O[C@H]1C(=O)O)C(=O)NCCCCNC(=N)N
IUPAC navn	(2R,3R)-3-[[(2S)-1-(4-carbamimidamidobutylamino)-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Molekylær formel	C15 H27 N5 O5

Melford E-64

Irreversibel cysteinproteasehæmmer af calpain, cathepsin (B,H,L,S), papain og andre cysteinproteaser.

Pris og tilgængelighed

E-64, MedChemExpress

MedChemExpress E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC50 of 9 nM for papain.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	E-64
Formel vægt	357.41
Opløselighedsinformation	DMSO : 100 mg/mL (279.79 mM; Need ultrasonic) ∣H2O : 5 mg/mL (13.99 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	357.41
CAS	66701-25-5
Synonym	Proteinase inhibitor E 64
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C([C@H]1O[C@@H]1C(N[C@H](C(NCCCCNC(N)=N)=O)CC(C)C)=O)O
Renhedsgrad noter	Research
Molekylær formel	C₁₅H₂₇N₅O₅
Til brug med (applikation)	COVID-19-immunoregulation

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