MedChemExpress Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Mirdametinib
Sundhedsfare 1	H301∣H413
Formel vægt	482.19
Opløselighedsinformation	DMSO : ≥ 56 mg/mL (116.14 mM)
Procent renhed	99.34%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	482.19
CAS	391210-10-9
Synonym	PD0325901 PD325901
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
Renhedsgrad noter	Research
Molekylær formel	C₁₆H₁₄F₃IN₂O₄
Til brug med (applikation)	Cancer-Kinase/protease

STEMCELL Technologies PD0325901

MEK/ERK pathway inhibitor; Inhibits MEK

Pris og tilgængelighed
Tekniske data

CAS	391210-10-9
Renhed	≥98%
Molekylær formel	C₁₆H₁₄F₃IN₂O₄

CAS RN 391210-10-9

Filtrerede søgeresultater

Snævre resultater

Tocris Bioscience™ PD 0325901 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ PD 0325901