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Mirdametinib, MedChemExpress

Artikelnummer. 16454806
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16454806 100 mg
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16406477 5 mg
16403748 10 mg
16402846 25 mg
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Artikelnummer. 16454806 Leverandør Medchem Express Leverandørnr. HY10254

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Beskrivelse

MedChemExpress Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Tekniske data

Kemisk navn eller materiale Mirdametinib
CAS 391210-10-9
Farve White
Renhedsgrad noter Research
Molekylær formel C16H14F3IN2O4
Mængde 100 mg
Synonym PD0325901 PD325901
Opløselighedsinformation DMSO : ≥ 56 mg/mL (116.14 mM)
SMIL O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
Molekylvægt (g/mol) 482.19
Formel vægt 482.19
Procent renhed 99.34%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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