Honeywell Hydranal™


Original and Innovative Karl Fischer Reagents

Looking to analyse or measure water content?

The premium Hydranal™ products for pyridine-free and ethanol-based water determination by Karl Fischer titration (KF titration) is comprised of  one- and two-component reagents for volumetric and reagents for coulometric Karl Fischer titrations. Also available are water standards for titer standardisation, pH buffering reagents, special reagents for aldehydes, ketones, and other solubilising agents.

Volumetric Karl Fischer Titration

Explore the many benefits of the broadest portfolio of one- and two-component volumetric reagents.

New formulation of Hydranal-Composite reagents improves stability and eliminates the formation of crystals.

Our broad selection includes:


Optimise your titration with the right reagents

Optimize your titration with the right reagents

Advantages of Hydranal one-component reagents:

  • Unlimited water capacity
  • Convenient and easy to use
  • The greatest flexibility in working media selections
  • Suitable for methanol-reacting compounds, e.g. ketones and aldehydes
  • Long shelf life (three years)

Improved Composition

Hydranal-Composite contains all the reactants including iodine, sulfur dioxide, and the bases imidazole and 2-methylimidazole, dissolved in diethylene glycol monoethyl ether (DEGEE). Adding 2-methylimidazole in addition to imidazole improves the stability and eliminates the formation of crystals which can interfere with the titrator’s performance.

The complete Karl Fischer titration solution from Honeywell

The complete KF Titration solution from Honeywell

Advantages of Hydranal two-component reagents:

  • High titration speed
  • Ideal accuracy for small amounts of water
  • High buffer capacity
  • Exact and stable titre
  • E-type reagents: reduced toxicity compared to methanol
  • Long shelf life (three years for titrants, five years for solvents)


In two-component reagents, the Karl Fischer reactants are separated into two solutions: the titrant and the solvent. Hydranal-Titrant contains iodine dissolved in an alcohol with a precisely defined concentration. Hydranal-Solvent is an alcoholic solution of sulfur dioxide and imidazole.

The alcohol is either methanol for standard reagents, or ethanol for E-type reagents.  

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Honeywell Research Chemicals
Coulometric KF Titration

Coulometric reagents based on different solvent compositions serve to support the broad variety of samples analysed.

All your Karl Fischer reagents from one source

All your KF regagents from one source

Some working techniques are supported by special reagents:


Advantages of Hydranal coulometric reagents:

  • Easy to use
  • High accuracy for trace amounts of water
  • Stable conditions of the titration vessel
  • Broad product range
  • Long shelf life (up to five years)

Hydranal-Coulomat A-type or E-type reagents are used as anolytes. The anolytes contain iodide and a sulfur dioxide/imidazole buffer in suitable solvents.

Hydranal-Coulomat CG reagents are used as catholytes.


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Water Standards

The Hydranal family offers verified water standards with exactly confirmed water content for:

  • Titre determination
  • Monitoring precision and accuracy
  • Validation and inspection of Karl Fischer titrators according to ISO, GMP, GLP and FDA guidelines

Advantages of Hydranal Water Standards:

  • Broad product range for volumetric and coulometric Karl Fischer applications
  • Manufactured according to current ISO requirements
  • Verified against NIST SRM 2890
  • Long shelf life (up to five years)
  • Convenient packaging
  • Supplied with detailed instructions for use
  • Certificate of Analysis with exact water content
  • Hydranal introduced the very first commercially available CRM (Certified Reference Material) Water Standards thanks to double accreditation (ISO/IEC 17025 and ISO Guide 34).

Unique water standards include:


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Other KF Titration products

Hydranal is offering a wide range of additional Karl Fischer titration products:

  • Solubilisers (Formamide dry, Chloroform, Xylene) to aid the working conditions and enable a direct titration of the sample
  • Buffers to neutralise acidic or basic samples to reach ideal pH value or suppress side reactions
  • Moisture Test Kits to determine the amount of water in various samples while being in the field or away from a Karl Fischer titrator

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Advantages of Hydranal Reagents:

• High titration speed

• Stable end points

• Accurate results

• Long shelf life

• Wide applicability

• World leading technical support

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