MedChemExpress Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Fedratinib
Formel vægt	524.68
Opløselighedsinformation	DMSO : 125 mg/mL (238.24 mM; Need ultrasonic)
Procent renhed	98.02%
Fysisk form	Powder
Farve	Light Nude
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	524.68
CAS	936091-26-8
Synonym	TG-101348 SAR 302503
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₇H₃₆N₆O₃S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 936091-26-8

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