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Fedratinib, MedChemExpress

Artikelnummer. 16443958
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Mængde:
5 mg
10 mg
100 mg
Pakningsstørrelse:
5mg
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Artikelnummer. Mængde unitSize
16443958 10 mg -
16426677 5 mg 5mg
16424976 100 mg -
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Artikelnummer. 16443958 Leverandør Medchem Express Leverandørnr. HY10409

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Beskrivelse

MedChemExpress Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

Tekniske data

Kemisk navn eller materiale Fedratinib
CAS 936091-26-8
Farve Light Nude
Renhedsgrad noter Research
Molekylær formel C27H36N6O3S
Mængde 10 mg
Synonym TG-101348 SAR 302503
Opløselighedsinformation DMSO : 125 mg/mL (238.24 mM; Need ultrasonic)
SMIL O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
Molekylvægt (g/mol) 524.68
Formel vægt 524.68
Procent renhed 98.02%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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