CAS RN 68844-77-9
Astemizole, TRC
CAS: 68844-77-9 Molekylær formel: C28 H31 F N4 O Molekylvægt (g/mol): 458.57 Synonym: 1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-,Astemisan,Astemizole,Hismanal,Histamen,Histaminos,Histazol,Kelp,Laridal,Metodik,NSC 329963,Novo-Nastizol A,Paralergin,R 42512,R 43512,Retolen,Waruzol IUPAC navn: 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine SMIL: COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1
Astemizole, MedChemExpress
MedChemExpress Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects.