CAS RN 548472-68-0

IUPAC Navn: 4-[4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one

Synonymer: nutlin

Molekylvægt (g/mol): 581.49

Molekylformel: C30H30Cl2N4O4

InChi Key: BDUHCSBCVGXTJM-UHFFFAOYNA-N

SMILES: COC1=CC=C(C2=NC(C(N2C(=O)N2CCNC(=O)C2)C2=CC=C(Cl)C=C2)C2=CC=C(Cl)C=C2)C(OC(C)C)=C1

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High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

CAS: 548472-68-0 Molekylær formel: C30H30Cl2N4O4

CAS	548472-68-0
Molekylær formel	C30H30Cl2N4O4

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

MedChemExpress Nutlin-3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM.

Kemisk navn eller materiale	Nutlin-3
Formel vægt	581.49
Opløselighedsinformation	Ethanol : 100 mg/mL (171.97 mM; Need ultrasonic) ∣DMSO : ≥ 50 mg/mL (85.99 mM)
Procent renhed	95.18%
Fysisk form	Powder
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	581.49
CAS	548472-68-0
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
Renhedsgrad noter	Research
Molekylær formel	C₃₀H₃₀Cl₂N₄O₄
Til brug med (applikation)	Cancer-programmed cell death

p53 pathway activator; Inhibits MDM2