MedChemExpress KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	KU-57788
Formel vægt	413.49
Opløselighedsinformation	DMSO : 14.29 mg/mL (34.56 mM; Need ultrasonic)
Procent renhed	98.85%
Fysisk form	Powder
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	413.49
CAS	503468-95-9
Synonym	NU7441
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C1C=C(N2CCOCC2)OC3=C1C=CC=C3C4=CC=CC5=C4SC6=C5C=CC=C6
Renhedsgrad noter	Research
Molekylær formel	C₂₅H₁₉NO₃S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 503468-95-9

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