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HClHClFNHNNONONHOCH2Cl

CAS RN 289499-45-2

IUPAC Navn: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide dihydrochloride
Synonymer: canertinib dihydrochloride
Molekylvægt (g/mol): 558.86
Molekylformel: C24H27Cl3FN5O3
InChi Key: JZZFDCXSFTVOJY-UHFFFAOYSA-N
SMILES: Cl.Cl.FC1=CC=C(NC2=C3C=C(NC(=O)C=C)C(OCCCN4CCOCC4)=CC3=NC=N2)C=C1Cl
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1

Canertinib dihydrochlorid, Thermo Scientific™

CAS: 289499-45-2 Molekylær formel: C24 H25 Cl F N5 O3 · 2 H Cl

CAS 289499-45-2
Molekylær formel C24 H25 Cl F N5 O3 · 2 H Cl
2

Tocris Bioscience™ Canertinib dihydrochloride
GREENER_CHOICE

Potent EGFR kinase inhibitor

Analyseprocentområde >98%
Kemisk navn eller materiale N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride
Anbefalet opbevaring Store at -20°C
CAS 289499-45-2
Formel vægt Observed MW: 558.86
Molekylær formel C24H25ClFN5O3.2HCl
3

Canertinib dihydrochloride, MedChemExpress

MedChemExpress Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Canertinib dihydrochloride
Sundhedsfare 1 H315∣H319∣H335
Formel vægt 558.86
Opløselighedsinformation DMSO : 62.5 mg/mL (111.83 mM; Need ultrasonic) ∣H2O : 25 mg/mL (44.73 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol) 558.86
CAS 289499-45-2
Synonym CI-1033 dihydrochloride PD-183805 dihydrochloride
Holdbarhed 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL C=CC(NC1=CC2=C(N=CN=C2C=C1OCCCN3CCOCC3)NC4=CC=C(C(Cl)=C4)F)=O.[H]Cl.[H]Cl
Renhedsgrad noter Research
Molekylær formel C24H27Cl3FN5O3
Til brug med (applikation) Cancer-Kinase/protease
4

Canertinib dihydrochloride, Tocris Bioscience™
GREENER_CHOICE

Potent EGFR kinase inhibitor

ENCOMPASS
5

Canertinib dihydrochloride, Tocris Bioscience™
GREENER_CHOICE

Potent EGFR kinase inhibitor

ENCOMPASS