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CAS RN 288383-20-0

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1

Cediranib, TRC

CAS: 288383-20-0 Molekylær formel: C25H27FN4O3 Molekylvægt (g/mol): 450.51 Synonym: 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline,4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline,4-(4-Fluoro-2-methylindol-5-yloxy)-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline,ZD 2171,AZD 2171 IUPAC navn: 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline SMIL: COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN5CCCC5

Molekylvægt (g/mol) 450.51
CAS 288383-20-0
Synonym 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline,4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline,4-(4-Fluoro-2-methylindol-5-yloxy)-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline,ZD 2171,AZD 2171
SMIL COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN5CCCC5
IUPAC navn 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
Molekylær formel C25H27FN4O3
2

Tocris Bioscience™ Cediranib
GREENER_CHOICE

Potent inhibitor of VEGFR, PDGFR and FGFR

Kemisk navn eller materiale 4-[(4-Fluoro-2-methyl-1 H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline
Anbefalet opbevaring Store at -20°C
CAS 288383-20-0
Mål VEGF Receptor Inhibitors
Renhed 0.98
Molekylær formel C25H27FN4O3
3

Cediranib, MedChemExpress

MedChemExpress Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Cediranib
Sundhedsfare 1 H302∣H315∣H319∣H335
Formel vægt 450.51
Opløselighedsinformation DMSO : 20 mg/mL (44.39 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 450.51
CAS 288383-20-0
Synonym AZD2171
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5
Renhedsgrad noter Research
Molekylær formel C25H27FN4O3
Til brug med (applikation) Cancer-Kinase/protease