CAS RN 1260075-17-9

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Mitapivat, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pris og tilgængelighed

Mitapivat, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pris og tilgængelighed

Mitapivat, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pris og tilgængelighed

MedChemExpress Mitapivat (AG-348) is a potent, orally active, and allosteric activator of pyruvate kinase with an AC50 of 20 nM. Mitapivat (AG-348) increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes. Mitapivat (AG-348) has the potential for restoring the glycolytic pathway activity with PK deficiency.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Mitapivat
Formel vægt	450.55
Opløselighedsinformation	DMSO : 20.83 mg/mL (46.23 mM; ultrasonic and warming and heat to 60°C)
Procent renhed	98.19%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	450.55
CAS	1260075-17-9
Synonym	AG-348
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₂₆N₄O₃S
Til brug med (applikation)	Cancer-Kinase/protease

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