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Tetracykliner

Organiske forbindelser omfattende en lineært fusioneret tetracyklisk rygrad, hvortil en række funktionelle grupper kan knyttes; de har et octahydrotetracen-2-carboxamidskelet og er kendt som derivater af polycyklisk naphthacencarboxamid.

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1 – 13 af 13 Resultater
1

N-Desmethyl Doxycycline, TRC

CAS: 86271-83-2 Molekylær formel: C21H22N2O8 Molekylvægt (g/mol): 430.41 Synonym: [4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha)]-1,4,4a,5,5a,6,11,12a-Octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-4-(methylamino)-1,11-dioxo-2-naphthacenecarboxamide SMIL: CN[C@H]1[C@@H]2[C@@H](O)[C@@H]3[C@@H](C)c4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N

Molekylvægt (g/mol) 430.41
CAS 86271-83-2
Synonym [4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha)]-1,4,4a,5,5a,6,11,12a-Octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-4-(methylamino)-1,11-dioxo-2-naphthacenecarboxamide
SMIL CN[C@H]1[C@@H]2[C@@H](O)[C@@H]3[C@@H](C)c4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N
Molekylær formel C21H22N2O8
4

Minocyclin hydrochlorid, MP Biomedicals™

CAS: 13614-98-7 Molekylær formel: C23H28ClN3O7 Molekylvægt (g/mol): 493.94 MDL nummer: MFCD00083669 InChI nøgle: KDLQIOPKJDNQIM-WUURTAMISA-N Synonym: minocycline hydrochloride,minocycline hcl,minomycin,minocin,minocycline chloride,arestin,vectrin,minomax,periocline,tri-mino PubChem CID: 54685925 IUPAC navn: hydrogen (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methyliden]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracen-1,3,12-chlorid SMIL: [H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(O)=C4C(O)=C3C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O)N(C)C

MDL nummer MFCD00083669
PubChem CID 54685925
Molekylvægt (g/mol) 493.94
CAS 13614-98-7
Synonym minocycline hydrochloride,minocycline hcl,minomycin,minocin,minocycline chloride,arestin,vectrin,minomax,periocline,tri-mino
SMIL [H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(O)=C4C(O)=C3C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O)N(C)C
IUPAC navn hydrogen (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methyliden]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracen-1,3,12-chlorid
InChI nøgle KDLQIOPKJDNQIM-WUURTAMISA-N
Molekylær formel C23H28ClN3O7
5
Kampagner er tilgængelige

Chlortetracyclin hydrochlorid, specificeret i henhold til kravene i Ph.Eur., Thermo Scientific Chemicals

CAS: 64-72-2 Molekylær formel: C22H23ClN2O8·HCl Molekylvægt (g/mol): 515.33 MDL nummer: MFCD00082440 InChI nøgle: QYAPHLRPFNSDNH-CIVPRPTRSA-N Synonym: chlortetracycline hydrochloride,4-epi-chlortetracycline hydrochloride,2-amino hydroxy methylidene-7-chloro-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride,2-azanyl oxidanyl methylidene-7-chloranyl-4-dimethylamino-6-methyl-6,10,11,12a-tetrakis oxidanyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride PubChem CID: 66577600 IUPAC navn: (4S,4aR,5aS,6S,12aR)-7-chlor-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracen-2-carboxamid;hydrochlorid SMIL: CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl

MDL nummer MFCD00082440
PubChem CID 66577600
Molekylvægt (g/mol) 515.33
CAS 64-72-2
Synonym chlortetracycline hydrochloride,4-epi-chlortetracycline hydrochloride,2-amino hydroxy methylidene-7-chloro-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride,2-azanyl oxidanyl methylidene-7-chloranyl-4-dimethylamino-6-methyl-6,10,11,12a-tetrakis oxidanyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride
SMIL CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl
IUPAC navn (4S,4aR,5aS,6S,12aR)-7-chlor-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracen-2-carboxamid;hydrochlorid
InChI nøgle QYAPHLRPFNSDNH-CIVPRPTRSA-N
Molekylær formel C22H23ClN2O8·HCl
6

Sancycline, MedChemExpress

MedChemExpress Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Sancycline
Formel vægt 414.41
Opløselighedsinformation DMSO : 8.33 mg/mL (20.10 mM; ultrasonic and warming and heat to 60°C)
Procent renhed 99.12%
Fysisk form Solid
Farve Earth Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 414.41
CAS 808-26-4
Synonym Bonomycin 6-Demethyl-6-deoxytetracycline
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
Renhedsgrad noter Research
Molekylær formel C21H22N2O7
Til brug med (applikation) COVID-19-immunoregulation
7

Omadacycline tosylate, MedChemExpress

MedChemExpress Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Omadacycline tosylate
Formel vægt 728.85
Opløselighedsinformation H2O : 12.5 mg/mL (17.15 mM; Need ultrasonic)
Procent renhed 99.37%
Fysisk form Powder
Farve Yellow
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
Molekylvægt (g/mol) 728.85
CAS 1075240-43-5
Synonym PTK 0796 tosylateAmadacycline tosylate
Holdbarhed 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
SMIL O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.OS(=O)(C5=CC=C(C)C=C5)=O
Renhedsgrad noter Research
Molekylær formel C36H48N4O10S
Til brug med (applikation) COVID-19-immunoregulation
8

Oxytetracycline, MedChemExpress

MedChemExpress Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Oxytetracycline
Sundhedsfare 1 H302∣H312∣H332∣H350∣H360
Formel vægt 460.43
Opløselighedsinformation DMSO : ≥ 50 mg/mL (108.59 mM) ∣H2O : 0.67 mg/mL (1.46 mM; Need ultrasonic)
Procent renhed 98.07%
Fysisk form Powder
Farve Light Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 460.43
CAS 79-57-2
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
Renhedsgrad noter Research
Molekylær formel C22H24N2O9
Til brug med (applikation) COVID-19-anti-virus
9

Omadacycline hydrochloride, MedChemExpress

MedChemExpress Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Omadacycline hydrochloride
Formel vægt 593.11
Opløselighedsinformation DMSO : 105 mg/mL (177.03 mM; Need ultrasonic) ∣H2O : ≥ 50 mg/mL (84.30 mM)
Procent renhed 98.02%
Fysisk form Solid
Farve Dark Brown
Grad Research
Anbefalet opbevaring -20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol) 593.11
CAS 1196800-39-1
Synonym PTK0796 hydrochloride Amadacycline hydrochloride
Holdbarhed -20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.Cl
Renhedsgrad noter Research
Molekylær formel C29H40N4O7.HCl
Til brug med (applikation) COVID-19-immunoregulation
10

Rolitetracycline, MedChemExpress

MedChemExpress Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic. Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal drug and a prodrug.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Rolitetracycline
Formel vægt 527.57
Opløselighedsinformation H2O : 10 mg/mL (18.95 mM; Need ultrasonic and warming) ∣Ethanol : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble) ∣DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
Procent renhed 95.0%
Fysisk form Solid
Farve Light Brown
Grad Research
Anbefalet opbevaring Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 527.57
CAS 751-97-3
Holdbarhed Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)NCN5CCCC5
Renhedsgrad noter Research
Molekylær formel C27H33N3O8
Til brug med (applikation) COVID-19-immunoregulation
11

Demeclocycline hydrochloride, MedChemExpress

MedChemExpress Demeclocycline hydrochloride is a tetracycline antibiotic; is an antibiotic in the treatment of Lyme disease, acne, and bronchitis.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Demeclocycline hydrochloride
Sundhedsfare 1 H317∣H350∣H360
Formel vægt 501.31
Opløselighedsinformation DMSO : 100 mg/mL (199.48 mM; Need ultrasonic) ∣H2O : 20 mg/mL (39.90 mM; Need ultrasonic and warming)
Procent renhed 95.09%
Fysisk form Powder
Farve Light Yellow
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol) 501.31
CAS 64-73-3
Holdbarhed 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@H](O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N.Cl
Renhedsgrad noter Research
Molekylær formel C21H22Cl2N2O8
Til brug med (applikation) COVID-19-immunoregulation
12

Doxycycline (hyclate), MedChemExpress

MedChemExpress Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Doxycycline (hyclate)
Formel vægt 512.94
Opløselighedsinformation DMSO : 240 mg/mL (467.89 mM; Need ultrasonic) ∣H2O : 125 mg/mL (243.69 mM; Need ultrasonic)
Procent renhed 98.0%
Fysisk form Powder
Farve Yellow
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
Molekylvægt (g/mol) 512.94
CAS 24390-14-5
Synonym Doxycycline hydrochloride hemiethanolate hemihydrate WC2031
Holdbarhed 4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
SMIL O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@@H](C)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N.Cl.[0.5H2O].[0.5C2H6O]
Renhedsgrad noter Research
Molekylær formel C22H24N2O8.1/2C2H6O.ClH.1/2H2O
Til brug med (applikation) COVID-19-immunoregulation
13

4-Epianhydrochlortetracycline hydrochloride, can be used as secondary standard, Thermo Scientific Chemicals

CAS: 158018-53-2 Molekylær formel: C22H21ClN2O7·HCl Molekylvægt (g/mol): 497.33 MDL nummer: MFCD00143313 InChI nøgle: ISGAAFMBTIWTEU-PXAZKYFKSA-N Synonym: 4-epianhydrochlortetracycline hydrochloride,4-epianhydrochlortetracycline hcl,epianhydrochlortetracycline hydrochloride,2z,4r,4as,12as-2-amino hydroxy methylidene-7-chloro-4-dimethylamino-10,11,12a-trihydroxy-6-methyl-4a,5-dihydro-4h-tetracene-1,3,12-trione hydrochloride,4r,4as,12ar-7-chloro-4-dimethylamino-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide-hydrogen chloride 1/1,4r,4as,12as-7-chloro-4-dimethylamino-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-4a,5-dihydro-4h-tetracene-2-carboxamide hydrochloride,4r-4,a,4a,a,12a,a-7-chloro-4-dimethylamino-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride PubChem CID: 54710413 IUPAC navn: (4R,4aS,12aR)-7-chloro-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride SMIL: CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C14)Cl)O)O)O)O)C(=O)N)N(C)C.Cl

MDL nummer MFCD00143313
PubChem CID 54710413
Molekylvægt (g/mol) 497.33
CAS 158018-53-2
Synonym 4-epianhydrochlortetracycline hydrochloride,4-epianhydrochlortetracycline hcl,epianhydrochlortetracycline hydrochloride,2z,4r,4as,12as-2-amino hydroxy methylidene-7-chloro-4-dimethylamino-10,11,12a-trihydroxy-6-methyl-4a,5-dihydro-4h-tetracene-1,3,12-trione hydrochloride,4r,4as,12ar-7-chloro-4-dimethylamino-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide-hydrogen chloride 1/1,4r,4as,12as-7-chloro-4-dimethylamino-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-4a,5-dihydro-4h-tetracene-2-carboxamide hydrochloride,4r-4,a,4a,a,12a,a-7-chloro-4-dimethylamino-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride
SMIL CC1=C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C14)Cl)O)O)O)O)C(=O)N)N(C)C.Cl
IUPAC navn (4R,4aS,12aR)-7-chloro-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide;hydrochloride
InChI nøgle ISGAAFMBTIWTEU-PXAZKYFKSA-N
Molekylær formel C22H21ClN2O7·HCl