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Progesterone, 98%, Thermo Scientific Chemicals
Progesterone, CAS # 57-83-0, is a naturally occurring hormone required for maintenance of the uterine endothelium and suppression of estrogens.
320.00 DKK - 2685.00 DKK
Chemical Identifiers
| CAS | 57-83-0 |
|---|---|
| Molecular Formula | C21H30O2 |
| Molecular Weight (g/mol) | 314.46 |
| MDL Number | MFCD00003658 |
| InChI Key | RJKFOVLPORLFTN-LEKSSAKUSA-N |
| Synonym | progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan |
| PubChem CID | 5994 |
| ChEBI | CHEBI:17026 |
| IUPAC Name | (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
| SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|
10368310
|
Thermo Scientific Acros
225650050 |
5 g | Glass bottle |
320.00 DKK
5g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
10328360
|
Thermo Scientific Acros
225650250 |
25 g | Glass bottle |
1015.00 DKK
25g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
10277303
|
Thermo Scientific Acros
225651000 |
100 g | Glass bottle |
2685.00 DKK
100g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Progesterone is a sex hormone required for suppression of estrogen signaling and is also involved in transcriptional activation
• Progesterone maintains the uterine endothelium and sustains pregnancy through suppression of muscle contractility
Applications
• Progesterone signaling is relevant to the study of breast cancer
Literature References
Kim, O.; Park, E.Y.; Kwon, S.Y.; Shin, S.; Emerson, R.E.; Shin, Y.H.; DeMayo, F.J.; Lydon, J.P.; Coffey, D.M.; Hawkins, S.M.; Quilliam, L.A.; Cheon, D.J.; Fernández, F.M.; Nephew, K.P.; Karpf, A.R.; Widschwendter, M.; Sood, A.K.; Bast, R.C. Jr.; Godwin, A.K.; Miller, K.D.; Cho, C.H.; Kim, J. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020, 117(50), 31993-32004.
Jain, V.; McDonald, S.D.; Mundle, W.R.; Farine, D. Guideline No. 398: Progesterone for Prevention of Spontaneous Preterm Birth. J Obstet Gynaecol Can. 2020, 42(6), 806-812.
Chemical Identifiers
| 57-83-0 | |
| 314.46 | |
| RJKFOVLPORLFTN-LEKSSAKUSA-N | |
| 5994 | |
| (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
| C21H30O2 | |
| MFCD00003658 | |
| progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan | |
| CHEBI:17026 | |
| CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
Specifications
| 57-83-0 | |
| Brown-Yellow to Yellow | |
| Authentic | |
| C21H30O2 | |
| 15, 7889 | |
| + 190 | |
| Solubility in water: insoluble. Other solubilities: soluble in alcohol,acetone,dioxane,conc. h2so4 | |
| CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C | |
| 314.46 | |
| CHEBI:17026 | |
| 98% | |
| Progesterone |
| 126°C to 131°C | |
| 0.5% max. (500 mg, 105°C, 2 hrs) | |
| 97.5% min. (HPLC) | |
| MFCD00003658 | |
| +190° (20°C c=1,ethanol) | |
| progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan | |
| RJKFOVLPORLFTN-LEKSSAKUSA-N | |
| (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | |
| 5994 | |
| 314.46 | |
| Crystalline Powder, Crystals or Chunks |
Safety and Handling
GHS H Statement:
Suspected of causing cancer.
GHS P Statement:
Use personal protective equipment as required.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
missing translation for 'einecsNumber' : 200-350-6
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Progesterone
Signal Word
- Warning
Hazard Category
- Carcinogenicity Category 2
Hazard Statement
- H351-Suspected of causing cancer.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
RUO – Research Use Only
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Product Title
Progesterone, 98%, Thermo Scientific Chemicals