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Progesterone, 98%, Thermo Scientific Chemicals
Progesterone, CAS # 57-83-0, is a naturally occurring hormone required for maintenance of the uterine endothelium and suppression of estrogens.
Brand: Thermo Scientific Acros 225650050
317.74 DKK valid until 2025-12-31
Use promo code "25339" to get your promotional price.
| Quantity | 5 g |
|---|---|
| Packaging | Glass bottle |
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This item is not returnable.
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Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Progesterone is a sex hormone required for suppression of estrogen signaling and is also involved in transcriptional activation
• Progesterone maintains the uterine endothelium and sustains pregnancy through suppression of muscle contractility
Applications
• Progesterone signaling is relevant to the study of breast cancer
Literature References
Kim, O.; Park, E.Y.; Kwon, S.Y.; Shin, S.; Emerson, R.E.; Shin, Y.H.; DeMayo, F.J.; Lydon, J.P.; Coffey, D.M.; Hawkins, S.M.; Quilliam, L.A.; Cheon, D.J.; Fernández, F.M.; Nephew, K.P.; Karpf, A.R.; Widschwendter, M.; Sood, A.K.; Bast, R.C. Jr.; Godwin, A.K.; Miller, K.D.; Cho, C.H.; Kim, J. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020, 117(50), 31993-32004.
Jain, V.; McDonald, S.D.; Mundle, W.R.; Farine, D. Guideline No. 398: Progesterone for Prevention of Spontaneous Preterm Birth. J Obstet Gynaecol Can. 2020, 42(6), 806-812.
Chemical Identifiers
| 57-83-0 | |
| 314.46 | |
| RJKFOVLPORLFTN-LEKSSAKUSA-N | |
| 5994 | |
| (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
| C21H30O2 | |
| MFCD00003658 | |
| progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan | |
| CHEBI:17026 | |
| CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
Specifications
| 57-83-0 | |
| Brown-Yellow to Yellow | |
| Authentic | |
| Glass bottle | |
| MFCD00003658 | |
| 15, 7889 | |
| + 190 | |
| Solubility in water: insoluble. Other solubilities: soluble in alcohol,acetone,dioxane,conc. h2so4 | |
| CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C | |
| 314.46 | |
| CHEBI:17026 | |
| 98% | |
| Progesterone |
| 126°C to 131°C | |
| 0.5% max. (500 mg, 105°C, 2 hrs) | |
| 97.5% min. (HPLC) | |
| C21H30O2 | |
| 5 g | |
| +190° (20°C c=1,ethanol) | |
| progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan | |
| RJKFOVLPORLFTN-LEKSSAKUSA-N | |
| (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | |
| 5994 | |
| 314.46 | |
| Crystalline Powder, Crystals or Chunks |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Progesterone
Signal Word
- Warning
Hazard Category
- Carcinogenicity Category 2
Hazard Statement
- H351-Suspected of causing cancer.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
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