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Paclitaxel, 99.5+%, Thermo Scientific™
Paclitaxel (CAS # 33069-62-4) is a microtubule inhibitor produced from the extract of the Pacific yew tree.
1253.75 DKK - 5932.92 DKK
Kemiske identifikatorer
| CAS | 33069-62-4 |
|---|---|
| Molekylær formel | C47H51NO14 |
| Molekylvægt (g/mol) | 853.92 |
| MDL nummer | MFCD00869953 |
| InChI nøgle | RCINICONZNJXQF-VAZQATRQSA-N |
| Synonym | paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel |
| PubChem CID | 133640187 |
| IUPAC navn | (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate |
| SMIL | CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 |
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktkode | Brand | Mængde | Pris | Antal & tilgængelighed | |||||
|
15495039
|
Thermo Scientific Alfa Aesar
J62734.MC |
100mg |
1253.75 DKK
100mg |
Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | |||||
|
15405049
|
Thermo Scientific Alfa Aesar
J62734.ME |
500mg |
3664.23 DKK
500mg |
Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | |||||
|
15485039
|
Thermo Scientific Alfa Aesar
J62734.03 |
1g |
5932.92 DKK
1g |
Venligst log indfor at købe denne vare. Brug for en webkonto? Register dig hos os i dag! | |||||
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- Paclitaxel is a tetracyclic diterpenoid isolated from the Pacific yew, Taxus brevifolia
- Paclitaxel acts as an antineoplastic agent by binding tubulin and preventing cell division
- Paclitaxel may also bind Bcl-2 and lead to disinhibition of apoptosis
Application
- Paclitaxel is used in the study of lung, breast, and ovarian cancers; it may be useful in the research of other cancer types
- It is suitable for cell culture, biochemistry, and molecular biology applications
Kemiske identifikatorer
| 33069-62-4 | |
| 853.92 | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| 133640187 | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 |
| C47H51NO14 | |
| MFCD00869953 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate |
Tekniske data
| Paclitaxel | |
| C47H51NO14 | |
| 1420457 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate | |
| 133640187 | |
| ≥99.5% |
| 33069-62-4 | |
| MFCD00869953 | |
| 14,6982 | |
| Soluble in DMSO (200mg/ml) or ethanol (40mg/ml); Soluble in dimethylsulfoxide,methanol,ethanol,acetonitrile,cremophor and dimehtylsulfamide; Sparingly soluble in aqueous buffer. | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 | |
| 853.92 | |
| 853.91 |
Sikkerhed og håndtering
GHS H Statement
H334-H341-H361-H318-H302-H312-H332-H335-H315-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Suspected of causing genetic defects.
Suspected of damaging fertility or the unborn child.
Causes serious eye damage.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
May cause respiratory irritation.
Causes skin irritation.
May cause an allergic skin reaction.
P201-P202-P261-P264b-P270-P271-P281-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P312-P330-P342+P311-P363-P501c
H302+H312+H332-H318-H334-H335-H361
missing translation for 'rtecsNumber' : DA8340700
missing translation for 'tsca' : No
Anbefalet opbevaring : Store at -20°C
- Paclitaxel
Signalord
- Fare
Farekategori
- LANGTIDSFARE FOR VANDMILJØET Kronisk kategori 4
- Alvorlige øjenskader/øjenirritation Kategori 1
- Reproduktionstoksicitet Kategori 2
- Hudætsning/hudirritation Kategori 2
- Hudsensibilisering Kategori 1
- Specifik målorgantoksicitet - enkelt eksponering Kategori 2
Faresætning
- H315-Forårsager hudirritation.
- H317-Kan forårsage allergisk hudreaktion.
- H318-Forårsager alvorlig øjenskade.
- H335-Kan forårsage irritation af luftvejene.
- H361-Mistænkt for at skade forplantningsevnen eller det ufødte barn.
- H413-Kan forårsage langvarige skadelige virkninger for vandlevende organismer.
Sikkerhedssætning
- P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
- P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
- P304+P340-VED INDÅNDING: Flyt personen til et sted med frisk luft og sørg for, at vejrtrækningen lettes.
- P305+P351+P338-VED KONTAKT MED ØJNENE: Skyl forsigtigt med vand i flere minutter. Fjern eventuelle kontaktlinser, hvis dette kan gøres let. Fortsæt skylning.
- P310-Ring omgående til en GIFTINFORMATION/læge/.
Supplerende oplysninger
- MIXTURE LIST-Contain: Paclitaxel
RUO – Research Use Only
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