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Paclitaxel, 99.5+%, Thermo Scientific™
Paclitaxel (CAS # 33069-62-4) is a microtubule inhibitor produced from the extract of the Pacific yew tree.
Brand: Thermo Scientific Alfa Aesar J62734.03
| Mængde | 1g |
|---|
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Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- Paclitaxel is a tetracyclic diterpenoid isolated from the Pacific yew, Taxus brevifolia
- Paclitaxel acts as an antineoplastic agent by binding tubulin and preventing cell division
- Paclitaxel may also bind Bcl-2 and lead to disinhibition of apoptosis
Application
- Paclitaxel is used in the study of lung, breast, and ovarian cancers; it may be useful in the research of other cancer types
- It is suitable for cell culture, biochemistry, and molecular biology applications
Kemiske identifikatorer
| 33069-62-4 | |
| 853.92 | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| 133640187 | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 |
| C47H51NO14 | |
| MFCD00869953 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate |
Tekniske data
| Paclitaxel | |
| C47H51NO14 | |
| 1g | |
| 14,6982 | |
| Soluble in DMSO (200mg/ml) or ethanol (40mg/ml); Soluble in dimethylsulfoxide,methanol,ethanol,acetonitrile,cremophor and dimehtylsulfamide; Sparingly soluble in aqueous buffer. | |
| CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1 | |
| 853.92 | |
| 853.91 |
| 33069-62-4 | |
| MFCD00869953 | |
| 1420457 | |
| paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel | |
| RCINICONZNJXQF-VAZQATRQSA-N | |
| (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate | |
| 133640187 | |
| ≥99.5% |
Produkttitel
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