CAS RN 934660-93-2

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MedChemExpress Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1.

Kemisk navn eller materiale	Cobimetinib
Formel vægt	531.31
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (188.21 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	98.79%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	531.31
CAS	934660-93-2
Synonym	GDC-0973 XL518
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₂₁F₃IN₃O₂
Til brug med (applikation)	Cancer-Kinase/protease