CAS RN 916151-99-0

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APTO-253, MedChemExpress

MedChemExpress APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	APTO-253
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	367.38
Opløselighedsinformation	DMSO : 60 mg/mL (163.32 mM; Need ultrasonic)
Procent renhed	98.15%
Fysisk form	Powder
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	367.38
CAS	916151-99-0
Synonym	LOR-253 LT-253
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6
Renhedsgrad noter	Research
Molekylær formel	C₂₂H₁₄FN₅
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 916151-99-0

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