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APTO-253, MedChemExpress

Artikelnummer. 16497076
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16497076 100 mg
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16449567 5 mg
16403077 50 mg
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Artikelnummer. 16497076 Leverandør Medchem Express Leverandørnr. HY16291

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Beskrivelse

MedChemExpress APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.

APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.

Tekniske data

Kemisk navn eller materiale APTO-253
CAS 916151-99-0
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C22H14FN5
Mængde 100 mg
Synonym LOR-253 LT-253
Opløselighedsinformation DMSO : 60 mg/mL (163.32 mM; Need ultrasonic)
SMIL CC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6
Molekylvægt (g/mol) 367.38
Formel vægt 367.38
Procent renhed 98.15%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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