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CH3SHNO(S)NH3OO

CAS RN 83730-53-4

IUPAC Navn: (2S)-2-azaniumyl-4-[butyl(imino)oxo-λ⁶-sulfanyl]butanoate
Synonymer: (2S)-2-ammonio-4-[butyl(imino)oxo-λ⁶-sulfanyl]butanoate
Molekylvægt (g/mol): 222.3
Molekylformel: C8H18N2O3S
InChi Key: KJQFBVYMGADDTQ-CVSPRKDYSA-N
SMILES: CCCCS(=N)(=O)CC[C@H]([NH3+])C([O-])=O
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L-Buthionine-(S,R)-sulfoximine, 99%

CAS: 83730-53-4 Molekylær formel: C8H18N2O3S Molekylvægt (g/mol): 222.31 MDL nummer: MFCD00067000 InChI nøgle: KJQFBVYMGADDTQ-CVSPRKDYSA-N Synonym: l-buthionine-sulfoximine,l-buthionine sulfoximine,2s-2-amino-4-butylsulfonimidoyl butanoic acid,l-buthionine-s,r-sulfoximine,l-buthionine s,r-sulfoximine,l-bso,butanoic acid, 2-amino-4-s-butylsulfonimidoyl-, 2s,l-buthionine sr-sulfoximine,buthionine-s,r-sulfoximine, l,l-buthionine-s,r-sulphoximine PubChem CID: 119565 IUPAC navn: (2S)-2-amino-4-(butylsulfonimidoyl)butansyre SMIL: CCCCS(=N)(=O)CCC(C(=O)O)N

MDL nummer MFCD00067000
PubChem CID 119565
Molekylvægt (g/mol) 222.31
CAS 83730-53-4
Synonym l-buthionine-sulfoximine,l-buthionine sulfoximine,2s-2-amino-4-butylsulfonimidoyl butanoic acid,l-buthionine-s,r-sulfoximine,l-buthionine s,r-sulfoximine,l-bso,butanoic acid, 2-amino-4-s-butylsulfonimidoyl-, 2s,l-buthionine sr-sulfoximine,buthionine-s,r-sulfoximine, l,l-buthionine-s,r-sulphoximine
SMIL CCCCS(=N)(=O)CCC(C(=O)O)N
IUPAC navn (2S)-2-amino-4-(butylsulfonimidoyl)butansyre
InChI nøgle KJQFBVYMGADDTQ-CVSPRKDYSA-N
Molekylær formel C8H18N2O3S
2

Tocris Bioscience™ L-Buthionine sulfoximine
GREENER_CHOICE

Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis

3

L-Buthionine-(S,R)-sulfoximine, TRC

CAS: 83730-53-4 Molekylær formel: C8 H18 N2 O3 S Molekylvægt (g/mol): 222.31 IUPAC navn: (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid SMIL: CCCCS(=N)(=O)CC[C@H](N)C(=O)O

Molekylvægt (g/mol) 222.31
CAS 83730-53-4
SMIL CCCCS(=N)(=O)CC[C@H](N)C(=O)O
IUPAC navn (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid
Molekylær formel C8 H18 N2 O3 S
4

L-Buthionine-(S,R)-sulfoximine, MedChemExpress

MedChemExpress L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

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