CAS RN 630124-46-8

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N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

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AST 487, MedChemExpress

MedChemExpress AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.

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Tekniske data

Kemisk navn eller materiale	AST 487
Formel vægt	529.56
Opløselighedsinformation	DMSO : ≥ 100 mg/mL (188.84 mM)
Procent renhed	99.2%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	529.56
CAS	630124-46-8
Synonym	NVP-AST 487
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3
Renhedsgrad noter	Research
Molekylær formel	C₂₆H₃₀F₃N₇O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 630124-46-8

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