CAS RN 601514-19-6

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Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

WNT pathway activator; Inhibits GSK3β

MedChemExpress TWS119 is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.

Kemisk navn eller materiale	TWS119
Formel vægt	318.33
Opløselighedsinformation	DMSO : ≥ 50 mg/mL (157.07 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	98.0%
Fysisk form	Powder
Farve	Off-White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	318.33
CAS	601514-19-6
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	OC1=CC=CC(OC2=C3C(NC(C4=CC=CC(N)=C4)=C3)=NC=N2)=C1
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₁₄N₄O₂
Til brug med (applikation)	Cancer-Kinase/protease