CAS RN 524684-52-4

IUPAC Navn: 4-[(2Z)-7-ethenyl-5-hydroxy-2,3-dihydro-1,3-benzoxazol-2-ylidene]-2-fluorocyclohexa-2,5-dien-1-one

Synonymer: prinaberel

Molekylvægt (g/mol): 271.25

Molekylformel: C15H10FNO3

InChi Key: FCXYSEXZEGPLGG-DHDCSXOGSA-N

SMILES: OC1=CC2=C(O\C(N2)=C2\C=CC(=O)C(F)=C2)C(C=C)=C1

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Tocris Bioscience™ ERB 041

CAS: 524684-52-4 Molekylær formel: C15H10FNO3

Pris og tilgængelighed
Tekniske data

CAS	524684-52-4
Molekylær formel	C15H10FNO3

MedChemExpress Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Prinaberel
Sundhedsfare 1	H302∣H319
Formel vægt	271.24
Opløselighedsinformation	DMSO : ≥ 40 mg/mL (147.47 mM)
Procent renhed	98.05%
Fysisk form	Solid
Farve	Light Gray
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	271.24
CAS	524684-52-4
Synonym	ERB-041
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	OC1=CC(C=C)=C(OC(C2=CC=C(O)C(F)=C2)=N3)C3=C1
Renhedsgrad noter	Research
Molekylær formel	C₁₅H₁₀FNO₃
Til brug med (applikation)	Cancer-programmed cell death

CAS RN 524684-52-4

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Tocris Bioscience™ ERB 041 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ ERB 041