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Bicuculline, MedChemExpress

MedChemExpress Bicuculline ((+)-Bicuculline; d-Bicuculline), as a convulsant alkaloid, is a competitive neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+-activated potassium (SK) channels and subsequently blocks the slow afterhyperpolarization (slow AHP) .

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Bicuculline
Sundhedsfare 1	H300∣H311+H331∣H400
Formel vægt	367.35
Opløselighedsinformation	DMSO : 50 mg/mL (136.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	98.0%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molekylvægt (g/mol)	367.35
CAS	485-49-4
Synonym	(+)-Bicuculline d-Bicuculline
Holdbarhed	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
SMIL	O=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
Renhedsgrad noter	Research
Molekylær formel	C₂₀H₁₇NO₆

CAS RN 485-49-4

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