CAS RN 423148-78-1

IUPAC Navn: 1-(3-chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione

Synonymer: 1-(3-chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione

Molekylvægt (g/mol): 351.67

Molekylformel: C14H7ClFN3O5

InChi Key: MSYMKEYWUWVZQY-UHFFFAOYSA-N

SMILES: [O-][N+](=O)C1=CC=C(O1)C=C1C(=O)NN(C1=O)C1=CC(Cl)=C(F)C=C1

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PYZD-4409, MedChemExpress

MedChemExpress PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	PYZD-4409
Sundhedsfare 1	H301∣H315∣H319∣H335
Formel vægt	351.67
Opløselighedsinformation	DMSO : ≥ 35 mg/mL (99.53 mM)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Light Brown to Black
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	351.67
CAS	423148-78-1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	FC1=CC=C(N2C(/C(C(N2)=O)=C\C3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl
Renhedsgrad noter	Research
Molekylær formel	C₁₄H₇ClFN₃O₅
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 423148-78-1

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