CAS RN 1942114-09-1

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MedChemExpress EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	EAI045
Formel vægt	383.4
Opløselighedsinformation	DMSO : 100 mg/mL (260.82 mM; Need ultrasonic)
Procent renhed	96.53%
Fysisk form	Solid
Farve	off White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	383.4
CAS	1942114-09-1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C(C1=C(O)C=CC(F)=C1)N2C(C(C=CC=C3)=C3C2)=O)NC4=NC=CS4
Renhedsgrad noter	Research
Molekylær formel	C₁₉H₁₄FN₃O₃S
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1942114-09-1

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