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EAI045, MedChemExpress

Artikelnummer. 16474256
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16474256 100 mg
16429506 50 mg
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Artikelnummer. 16474256 Leverandør Medchem Express Leverandørnr. HY100213

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Description

MedChemExpress EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.

EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.

Specifications

Kemisk navn eller materiale EAI045
CAS 1942114-09-1
Farve off White
Renhedsgrad noter Research
Molekylær formel C19H14FN3O3S
Mængde 100 mg
Opløselighedsinformation DMSO : 100 mg/mL (260.82 mM; Need ultrasonic)
SMIL O=C(C(C1=C(O)C=CC(F)=C1)N2C(C(C=CC=C3)=C3C2)=O)NC4=NC=CS4
Molekylvægt (g/mol) 383.4
Formel vægt 383.4
Procent renhed 96.53%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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