CAS RN 184475-55-6

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Gefitinib hydrochloride, MedChemExpress

MedChemExpress Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Gefitinib hydrochloride
Formel vægt	483.36
Opløselighedsinformation	H2O : 6.25 mg/mL (12.93 mM; Need ultrasonic) ∣DMSO : 0.227 mg/mL (0.47 mM; Need ultrasonic and warming)
Procent renhed	99.8%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	483.36
CAS	184475-55-6
Synonym	ZD-1839 hydrochloride
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₂₂H₂₅Cl₂FN₄O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 184475-55-6

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