CAS RN 1532533-78-0

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Umbralisib hydrochloride, MedChemExpress

MedChemExpress Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Umbralisib hydrochloride
Formel vægt	608.01
Opløselighedsinformation	DMSO : ≥ 150 mg/mL (246.71 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	98.98%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	608.01
CAS	1532533-78-0
Synonym	TGR-1202 hydrochloride RP5264 hydrochloride
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16.[H]Cl
Renhedsgrad noter	Research
Molekylær formel	C₃₁H₂₅ClF₃N₅O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1532533-78-0

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