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Umbralisib hydrochloride, MedChemExpress

Artikelnummer. 16477777
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16477777 5 mg
16455796 100 mg
16445058 10 mg
16421297 50 mg
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Artikelnummer. 16477777 Leverandør Medchem Express Leverandørnr. HY12279C

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Beskrivelse

MedChemExpress Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.

Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.

Tekniske data

Kemisk navn eller materiale Umbralisib hydrochloride
CAS 1532533-78-0
Farve White
Renhedsgrad noter Research
Molekylær formel C31H25ClF3N5O3
Mængde 5 mg
Synonym TGR-1202 hydrochloride RP5264 hydrochloride
Opløselighedsinformation DMSO : ≥ 150 mg/mL (246.71 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL O=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16.[H]Cl
Molekylvægt (g/mol) 608.01
Formel vægt 608.01
Procent renhed 98.98%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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