CAS RN 1256580-46-7
IUPAC Navn:
9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile
Synonymer:
alectinib
Molekylvægt (g/mol):
482.63
Molekylformel:
C30H34N4O2
InChi Key:
KDGFLJKFZUIJMX-UHFFFAOYSA-N
SMILES:
CCC1=C(C=C2C(=C1)C(=O)C1=C(NC3=CC(=CC=C13)C#N)C2(C)C)N1CCC(CC1)N1CCOCC1
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CH5424802, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
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CH5424802, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
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CH5424802, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
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Alectinib, MedChemExpress
MedChemExpress Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
