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Alectinib, MedChemExpress

Artikelnummer. 16481056
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16481056 200 mg
16465478 10 mg
16456066 100 mg
16431657 50 mg
16418197 5 mg
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Artikelnummer. 16481056 Leverandør Medchem Express Leverandørnr. HY13011

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Beskrivelse

MedChemExpress Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

Tekniske data

Kemisk navn eller materiale Alectinib
CAS 1256580-46-7
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C30H34N4O2
Mængde 200 mg
Synonym CH5424802 RO5424802 AF802
Opløselighedsinformation DMSO : 6.2 mg/mL (12.85 mM; Need warming)
SMIL N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
Molekylvægt (g/mol) 482.62
Formel vægt 482.62
Procent renhed 98.2%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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