CAS RN 1234015-52-1

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Prexasertib, MedChemExpress

MedChemExpress Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Prexasertib
Formel vægt	365.39
Opløselighedsinformation	DMSO : 16.67 mg/mL (45.62 mM; Need ultrasonic)
Procent renhed	98.03%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	365.39
CAS	1234015-52-1
Synonym	LY2606368
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	NCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₁₉N₇O₂
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 1234015-52-1

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