CAS RN 1188910-76-0

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MedChemExpress Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.

Kemisk navn eller materiale	Agerafenib
Formel vægt	517.46
Opløselighedsinformation	DMSO : 50 mg/mL (96.63 mM; Need ultrasonic)
Procent renhed	99.53%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	517.46
CAS	1188910-76-0
Synonym	CEP-32496 RXDX-105
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2
Renhedsgrad noter	Research
Molekylær formel	C₂₄H₂₂F₃N₅O₅
Til brug med (applikation)	Cancer-Kinase/protease