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Phenylacetic acids

Organic compounds that consist of a phenyl group with a carboxylic acid group substitution; a carboxylic acid contains a carbon atom bonded to both a carbonyl group and a hydroxyl group.

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1 – 5 af 5 Resultater
1

AM211, MedChemExpress

MedChemExpress AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale AM211
Formel vægt 500.51
Opløselighedsinformation DMSO : ≥ 125 mg/mL (249.75 mM)
Procent renhed 98.11%
Fysisk form Solid
Farve White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 500.51
CAS 1175526-27-8
Synonym AM211 free acid
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)CC1=CC(C2=CC=C(C(F)(F)F)C=C2CN(CC)C(NCC3=CC=CC=C3)=O)=C(OC)C=C1
Renhedsgrad noter Research
Molekylær formel C27H27F3N2O4
Til brug med (applikation) COVID-19-immunoregulation
2

TES-1025, MedChemExpress

MedChemExpress TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale TES-1025
Formel vægt 383.44
Opløselighedsinformation DMSO : 100 mg/mL (260.80 mM; Need warming)
Procent renhed 95.11%
Fysisk form Solid
Farve Yellow
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 383.44
CAS 1883602-21-8
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C1C(C#N)=C(C2=CC=CS2)N=C(SCC3=CC=CC(CC(O)=O)=C3)N1
Renhedsgrad noter Research
Molekylær formel C18H13N3O3S2
Til brug med (applikation) Metabolism-protein/nucleotide metabolism
3

Evocalcet, MedChemExpress

MedChemExpress Evocalcet has an activating effect on calcium sensing receptor (CaSR) extracted from patent WO 2017061621 A1, compound A.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Evocalcet
Formel vægt 374.48
Opløselighedsinformation DMSO : 30 mg/mL (80.11 mM; Need ultrasonic and warming)
Procent renhed 99.05%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 374.48
CAS 870964-67-3
Synonym KHK7580
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)CC1=CC=C(N2C[C@@H](N[C@@H](C3=C4C=CC=CC4=CC=C3)C)CC2)C=C1
Renhedsgrad noter Research
Molekylær formel C24H26N2O2
Til brug med (applikation) Metabolism-protein/nucleotide metabolism
4

AM095 free acid, MedChemExpress

MedChemExpress AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale AM095 free acid
Formel vægt 456.49
Opløselighedsinformation DMSO : 67.3 mg/mL (147.43 mM; Need ultrasonic and warming)
Procent renhed 98.07%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol) 456.49
CAS 1228690-36-5
Holdbarhed Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4)C)=O)C(C)=NO3)C=C2)C=C1
Renhedsgrad noter Research
Molekylær formel C27H24N2O5
Til brug med (applikation) COVID-19-immunoregulation
5

Diclofenac diethylamine, MedChemExpress

MedChemExpress Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

ENCOMPASS_PREFERRED
Kemisk navn eller materiale Diclofenac diethylamine
Formel vægt 369.29
Opløselighedsinformation DMSO : 150 mg/mL (406.18 mM; Need ultrasonic)
Procent renhed 99.55%
Fysisk form Solid
Farve Off-White
Grad Research
Anbefalet opbevaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol) 369.29
CAS 78213-16-8
Holdbarhed 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl.CCNCC
Renhedsgrad noter Research
Molekylær formel C18H22Cl2N2O2
Til brug med (applikation) COVID-19-immunoregulation