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Invitrogen™ Human TEK (TIE2) [Y897S], GST Tag Recombinant Protein

Recombinant Protein

4245.00 DKK - 61400.00 DKK

Specifications

Accession Number	Q02763
Concentration	See Label
For Use With (Application)	Kinase Assay
Formulation	50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez)	7010

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Products 3

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
15920293 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A30519	10 μg	4245.00 DKK 10µg		Please sign in to purchase this item. Need a web account? Register with us today!

17118745 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A32878	100 μg	19780.00 DKK 100µg		Please sign in to purchase this item. Need a web account? Register with us today!

17148785 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A33368	1 mg	61400.00 DKK 1mg		Please sign in to purchase this item. Need a web account? Register with us today!

Description

TEK (TIE2) Y897S receptor tyrosine kinase is expressed principally on vascular endothelium. Disrupting TEK Y897S function in mice results in embryonic lethality with defects in embryonic vasculature, suggesting a role in blood vessel maturation and maintenance. Angiopoietin-1 is a secreted growth factor that binds to and activates the TEK receptor tyrosine kinase. SHP2 and GRB2 are recruited to the activated TEK kinase domain and are part of the cellular responses that mediate TEK function. TEK expression is upregulated in the endothelium of vascular 'hot spots' in human breast cancer specimens. However, TEK is also overexpressed in areas of active angiogenesis in normal tissues.

Specifications

Accession Number	Q02763
For Use With (Application)	Kinase Assay
Gene ID (Entrez)	7010
Name	Human TEK (TIE2) [Y897S], GST Tag
Common Name	TIE2 (TEK) (Y897S Mutant)
Protein Length	771-end
Species	Human
Protein Tag	GST-tag
Shipping Condition	Dry Ice
Form	Liquid

Concentration	See Label
Formulation	50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Molecular Weight (g/mol)	66.7 kDa
Gene Alias	TIE2
KinaseFamily	TIE Kinase Family
Conjugate	Unconjugated
Recombinant	Recombinant
Content And Storage	-80°C, Avoid Freeze/Thaw Cycles
Expression System	Insect cells

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Invitrogen™ Human TEK (TIE2) [Y897S], GST Tag Recombinant Protein

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Invitrogen™ Human TEK (TIE2) [Y897S], GST Tag Recombinant Protein

Specifications

Description

Specifications

Documents