CAS RN 355025-24-0
CAS RN 355025-24-0
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Medchem Express Ki16425, MedChemExpress
MedChemExpress Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells.
2
Tocris Ki 16425
LPA1 and LPA3 receptor antagonist