CAS RN 958852-01-2

IUPAC Navn: 5-{[4-(pyridin-4-yl)quinolin-6-yl]methylidene}-1,3-thiazolidine-2,4-dione

Synonymer: 5-{[4-(pyridin-4-yl)quinolin-6-yl]methylidene}-1,3-thiazolidine-2,4-dione

Molekylvægt (g/mol): 333.37

Molekylformel: C18H11N3O2S

InChi Key: QDITZBLZQQZVEE-UHFFFAOYSA-N

SMILES: O=C1NC(=O)C(S1)=CC1=CC=C2N=CC=C(C3=CC=NC=C3)C2=C1

1 – 1 af 1 Resultater

MedChemExpress GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively.

Kemisk navn eller materiale	GSK1059615
Formel vægt	333.36
Opløselighedsinformation	DMSO : 5 mg/mL (15.00 mM; Need ultrasonic)
Procent renhed	98.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	333.36
CAS	958852-01-2
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(S/C1=C\C2=CC=C3N=CC=C(C3=C2)C4=CC=NC=C4)NC1=O
Renhedsgrad noter	Research
Molekylær formel	C₁₈H₁₁N₃O₂S
Til brug med (applikation)	Cancer-Kinase/protease