CAS RN 936890-98-1

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MedChemExpress OSI-027 (ASP7486) is a potent, selective, orally active and ATP-competitive mTOR kinase activity inhibitor with an IC50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC50s of 22 nM and 65 nM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	OSI-027
Formel vægt	406.44
Opløselighedsinformation	DMSO : 125 mg/mL (307.55 mM; Need ultrasonic)
Procent renhed	95.75%
Fysisk form	Solid
Farve	Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	406.44
CAS	936890-98-1
Synonym	ASP7486
Holdbarhed	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C([C@H]1CC[C@H](C2=NC(C(N3)=CC4=C3C(OC)=CC=C4)=C5C(N)=NC=NN52)CC1)O
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₂₂N₆O₃
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 936890-98-1

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