CAS RN 912545-86-9

IUPAC Navn: 3-chloro-N-[4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide

Synonymer: smoothened agonist

Molekylvægt (g/mol): 490.06

Molekylformel: C28H28ClN3OS

InChi Key: VFSUUTYAEQOIMW-UHFFFAOYSA-N

SMILES: CNC1CCC(CC1)N(CC1=CC(=CC=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1

Molekylvægt (g/mol)

1 – 3 af 3 Resultater

1

Thermo Scientific™ SAG

Pris og tilgængelighed

2

STEMCELL Technologies SAG

Hedgehog pathway activator; Activates Smoothened (SMO)

ENCOMPASS_PREFERRED

Pris og tilgængelighed
Tekniske data

CAS	912545-86-9
Synonym	Smoothened Agonist
Renhed	≥98%
Molekylær formel	C₂₈H₂₈ClN₃OS

3

SAG, MedChemExpress

MedChemExpress SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo.

ENCOMPASS_PREFERRED

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	SAG
Sundhedsfare 1	H302∣H315∣H319∣H335
Formel vægt	490.06
Opløselighedsinformation	DMSO : ≥ 38 mg/mL (77.54 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Procent renhed	99.51%
Fysisk form	Solid
Farve	Off-White
Grad	Research
Anbefalet opbevaring	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molekylvægt (g/mol)	490.06
CAS	912545-86-9
Holdbarhed	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
SMIL	O=C(C1=C(Cl)C2=CC=CC=C2S1)N([C@H]3CC[C@H](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₈H₂₈ClN₃OS
Til brug med (applikation)	Cancer-programmed cell death