CAS RN 912445-05-7

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High affinity PARP-1 and -2 inhibitor; orally bioavailable

MedChemExpress Veliparib (dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Kis of 5.2 nM and 2.9 nM in cell-free assays, respectively.

Kemisk navn eller materiale	Veliparib dihydrochloride
Formel vægt	317.21
Opløselighedsinformation	H2O : 250 mg/mL (788.12 mM; Need ultrasonic) ∣DMSO : ≥ 3.2 mg/mL (10.09 mM)
Procent renhed	99.27%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molekylvægt (g/mol)	317.21
CAS	912445-05-7
Synonym	ABT-888 dihydrochloride
Holdbarhed	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
SMIL	O=C(C1=C2NC([C@@]3(NCCC3)C)=NC2=CC=C1)N.Cl.Cl
Renhedsgrad noter	Research
Molekylær formel	C₁₃H₁₈Cl₂N₄O
Til brug med (applikation)	Cancer-programmed cell death