CAS RN 885060-09-3
IUPAC Navn:
2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-2,3-dihydro-1,3,4-thiadiazole-3-carboxamide
Synonymer:
filanesib
Molekylvægt (g/mol):
420.48
Molekylformel:
C20H22F2N4O2S
InChi Key:
LLXISKGBWFTGEI-UHFFFAOYNA-N
SMILES:
CON(C)C(=O)N1N=C(SC1(CCCN)C1=CC=CC=C1)C1=C(F)C=CC(F)=C1
1
–
2
af
2
Resultater
2
Filanesib, MedChemExpress
MedChemExpress Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity.