CAS RN 859212-16-1

IUPAC Navn: N-[3-({[4,5'-bipyrimidin]-2-yl}amino)-4-methylphenyl]-4-{[3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide

Synonymer: N-(3-{[4,5'-bipyrimidin]-2-ylamino}-4-methylphenyl)-4-{[3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide

Molekylvægt (g/mol): 576.63

Molekylformel: C30H31F3N8O

InChi Key: ZGBAJMQHJDFTQJ-UHFFFAOYNA-N

SMILES: CN(C)C1CCN(CC2=C(C=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CN=C3)=C(C)C=C2)C(F)(F)F)C1

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Thermo Scientific™ Bafetinib, 95%

Pris og tilgængelighed

Bafetinib, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pris og tilgængelighed

Bafetinib, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pris og tilgængelighed

MedChemExpress Bafetinib is a potent and orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib augments the activities of several proapoptotic Bcl-2 homology (BH)3-only proteins (Bim, Bad, Bmf and Bik) and induces apoptosis in Ph+ leukemia cells via Bcl-2 family-regulated intrinsic apoptosis pathway.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Bafetinib
Formel vægt	576.62
Opløselighedsinformation	DMSO : 100 mg/mL (173.42 mM; Need ultrasonic)
Procent renhed	99.18%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	576.62
CAS	859212-16-1
Synonym	INNO-406 NS-187
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3
Renhedsgrad noter	Research
Molekylær formel	C₃₀H₃₁F₃N₈O
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 859212-16-1

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