CAS RN 851723-84-7

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MedChemExpress Timapiprant (OC000459) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant (OC000459) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant (OC000459) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Timapiprant
Formel vægt	348.37
Opløselighedsinformation	DMSO : 10 mg/mL (28.71 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	98.02%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molekylvægt (g/mol)	348.37
CAS	851723-84-7
Synonym	OC000459
Holdbarhed	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
SMIL	O=C(O)CN1C(C)=C(CC2=NC3=CC=CC=C3C=C2)C4=C1C=CC(F)=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₁H₁₇FN₂O₂
Til brug med (applikation)	COVID-19-immunoregulation

CAS RN 851723-84-7

CAS RN 851723-84-7

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