CAS RN 839707-37-8

IUPAC Navn: N-(3-{7-[(1,3-dimethyl-1H-pyrazol-5-yl)amino]-1-methyl-2-oxo-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl}-4-methylphenyl)-3-(trifluoromethyl)benzamide

Synonymer: N-(3-{7-[(2,5-dimethylpyrazol-3-yl)amino]-1-methyl-2-oxo-4H-[1,3]diazino[4,5-d]pyrimidin-3-yl}-4-methylphenyl)-3-(trifluoromethyl)benzamide

Molekylvægt (g/mol): 550.55

Molekylformel: C27H25F3N8O2

InChi Key: NBZFRTJWEIHFPF-UHFFFAOYSA-N

SMILES: CN1N=C(C)C=C1NC1=NC=C2CN(C(=O)N(C)C2=N1)C1=C(C)C=CC(NC(=O)C2=CC(=CC=C2)C(F)(F)F)=C1

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Pluripotin, MedChemExpress

MedChemExpress Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Pluripotin
Formel vægt	550.54
Opløselighedsinformation	DMSO : ≥ 33 mg/mL (59.94 mM)
Procent renhed	98.19%
Fysisk form	Solid
Farve	White
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	550.54
CAS	839707-37-8
Synonym	SC1
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	CN1C(NC2=NC=C3C(N(C)C(N(C4=CC(NC(C5=CC=CC(C(F)(F)F)=C5)=O)=CC=C4C)C3)=O)=N2)=CC(C)=N1
Renhedsgrad noter	Research
Molekylær formel	C₂₇H₂₅F₃N₈O₂
Til brug med (applikation)	Cancer-Kinase/protease

STEMCELL Technologies Pluripotin

PI3K and MEK/ERK pathway inhibitor; Inhibits RasGAP and ERK1

Pris og tilgængelighed
Tekniske data

CAS	839707-37-8
Synonym	SC-1
Renhed	≥98%
Molekylær formel	C₂₇H₂₅F₃N₈O₂

CAS RN 839707-37-8

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