Kemisk navn eller materiale	4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Anbefalet opbevaring	Store at -20°C
CAS	790299-79-5
Mål	CD117/c-kit
Renhed	0.98
Molekylær formel	C₂₈H₃₀N₆OS

MedChemExpress Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity.

Pris og tilgængelighed
Tekniske data

Kemisk navn eller materiale	Masitinib
Formel vægt	498.64
Opløselighedsinformation	DMSO : 100 mg/mL (200.55 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Procent renhed	95.0%
Fysisk form	Solid
Farve	Light Yellow
Grad	Research
Anbefalet opbevaring	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molekylvægt (g/mol)	498.64
CAS	790299-79-5
Synonym	AB1010
Holdbarhed	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMIL	O=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4
Renhedsgrad noter	Research
Molekylær formel	C₂₈H₃₀N₆OS
Til brug med (applikation)	Cancer-Kinase/protease

CAS RN 790299-79-5

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Tocris Bioscience™ Masitinib Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ Masitinib